article Open AccessTop 1% cited
Early Exposure to Anesthesia and Learning Disabilities in a Population-based Birth Cohort
Anesthesiology · 2009 · Vol. 110(4) · pp. 796–804
Robert T. Wilder✉(Marymount University)Randall P. Flick(Marymount University)Juraj Šprung(Marymount University)Slavica K. KatusicWilliam J. BarbaresiChristopher MickelsonStephen J. GleichDarrell R. SchroederAmy L. WeaverDavid O. Warner(Marymount University)
Abstract
Exposure to anesthesia was a significant risk factor for the later development of LD in children receiving multiple, but not single anesthetics. These data cannot reveal whether anesthesia itself may contribute to LD or whether the need for anesthesia is a marker for other unidentified factors that contribute to LD.
Anesthesia and Neurotoxicity ResearchCardiac, Anesthesia and Surgical OutcomesAnesthesia and Sedative AgentsMedicineHazard ratioConfidence intervalGestational ageAnestheticProportional hazards modelCohortPopulationRetrospective cohort studyCohort study
MeSH terms
AdolescentAge FactorsAnesthesia, GeneralChild, PreschoolFathersFemaleHumansLearning DisabilitiesMaleMinnesotaMothersNeuropsychological TestsPregnancyPregnancy ComplicationsRetrospective Studies
Citations
1,368
FWCI
30.40
field-weighted impact
References
41
Percentile
100%
vs. same field & year
Citations per year
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References
Neurodevelopmental status at eight years in children with dextro-transposition of the great arteries: The Boston Circulatory Arrest Trial
Journal of Thoracic and Cardiovascular Surgery · 2003 · 668 citations
Early Exposure to Common Anesthetic Agents Causes Widespread Neurodegeneration in the Developing Rat Brain and Persistent Learning Deficits
Journal of Neuroscience · 2003 · 1,977 citations
Critical periods of vulnerability for the developing nervous system: evidence from humans and animal models.
Environmental Health Perspectives · 2000 · 2,845 citations
History of the Rochester Epidemiology Project
Mayo Clinic Proceedings · 1996 · 1,455 citations
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