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Early Childhood Exposure to Anesthesia and Risk of Developmental and Behavioral Disorders in a Sibling Birth Cohort
Anesthesia & Analgesia · 2011 · Vol. 113(5) · pp. 1143–1151
Abstract
The risk of being subsequently diagnosed with developmental and behavioral disorders in children who were enrolled in a state Medicaid program and who had surgery when they were younger than 3 years was 60% greater than that of a similar group of siblings who did not undergo surgery. More tightly matched pairwise analyses indicate that the extent to which the excess risk is causally attributable to anesthesia or mediated by unmeasured factors remains to be determined.
Anesthesia and Neurotoxicity ResearchCardiac, Anesthesia and Surgical OutcomesAnesthesia and Sedative AgentsMedicineCohortSiblingPediatricsCohort studyRetrospective cohort studyIncidence (geometry)SurgeryInternal medicine
MeSH terms
AnesthesiaAnesthesia, GeneralAttention Deficit Disorder with HyperactivityAutistic DisorderChildChild Behavior DisordersDevelopmental DisabilitiesChild, PreschoolHumansInfantInfant, NewbornRetrospective StudiesUnited StatesCenters for Medicare and Medicaid Services, U.S.Cohort Studies
Citations
516
FWCI
15.85
field-weighted impact
References
36
Percentile
99%
vs. same field & year
Citations per year
Cited by
Propofol-induced apoptosis of neurones and oligodendrocytes in fetal and neonatal rhesus macaque brain
British Journal of Anaesthesia · 2013 · 469 citations
References
Race Differences in the Age at Diagnosis Among Medicaid-Eligible Children With Autism
Journal of the American Academy of Child & Adolescent Psychiatry · 2002 · 688 citations
Early Exposure to Anesthesia and Learning Disabilities in a Population-based Birth Cohort
Anesthesiology · 2009 · 1,368 citations
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