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TGF-β1 and radiation fibrosis: a master switch and a specific therapeutic target?

Michèle T. MartinJean-Louis LefaixS. Delanian
Effects of Radiation ExposureManagement of metastatic bone diseaseCancer Diagnosis and TreatmentFibrosisMedicineTransforming growth factorMyofibroblastContext (archaeology)Cancer researchGrowth factorWound healingRadiation therapyTransforming growth factor beta

MeSH terms

AnimalsCell DivisionCells, CulturedDrug Therapy, CombinationFibroblastsFibrosisHumansImmunity, CellularIntestinesLungRadiation InjuriesRadiodermatitisRNA, MessengerSkinSwine
Citations
642
FWCI
20.66
field-weighted impact
References
137
Percentile
100%
vs. same field & year
Citations per year
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References
Cellular basis of radiation-induced fibrosis
Radiotherapy and Oncology · 1995 · 365 citations
A perpetual cascade of cytokines postirradiation leads to pulmonary fibrosis
International Journal of Radiation Oncology*Biology*Physics · 1995 · 646 citations
Myofibroblasts. I. Paracrine cells important in health and disease
American Journal of Physiology-Cell Physiology · 1999 · 909 citations
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