articleTop 1% cited
Maternal hypothyroxinaemia during early pregnancy and subsequent child development: a 3‐year follow‐up study
Clinical Endocrinology · 2003 · Vol. 59(3) · pp. 282–288
Victor J. Pop✉(Tilburg University)Evelien Brouwers(Tilburg University)Huib L. Vader(Eindhoven University of Technology)Thomas VulsmaAnneloes L. van Baar(Institute of Developmental Physiology)J J de Vijlder(University of Amsterdam)
Abstract
Maternal hypothyroxinaemia during early gestation is an independent determinant of a delay in infant neurodevelopment. However, when fT4 concentrations increase during pregnancy in women who are hypothyroxinaemic during early gestation, infant development appears not to be adversely affected.
Thyroid Disorders and TreatmentsNeonatal Health and BiochemistryNeuroscience of respiration and sleepGestationBayley Scales of Infant DevelopmentMedicineThyroid functionPregnancyPercentileProspective cohort studyObstetricsPediatricsThyroid
MeSH terms
AdultChild DevelopmentChild, PreschoolEpidemiologic MethodsFemaleGestational AgeHumansHypothyroidismInfantMalePregnancyPregnancy ComplicationsResearch DesignThyroxine
Citations
730
FWCI
11.45
field-weighted impact
References
36
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99%
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References
The Regulation of Thyroid Function in Pregnancy: Pathways of Endocrine Adaptation from Physiology to Pathology
Endocrine Reviews · 1997 · 1,239 citations
Low maternal free thyroxine concentrations during early pregnancy are associated with impaired psychomotor development in infancy
Clinical Endocrinology · 1999 · 1,007 citations
The incidence of thyroid disorders in the community: a twenty‐year follow‐up of the Whickham Survey
Clinical Endocrinology · 1995 · 2,438 citations
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