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VLA Proteins in the Integrin Family: Structures, Functions, and Their Role on Leukocytes

Annual Review of Immunology · 1990 · Vol. 8(1) · pp. 365–400
Martin E. Hemler

Abstract

Exhausted CD8 T (Tex) cells are a distinct cell lineage that arise during chronic infections and cancers in animal models and humans. Tex cells are characterized by progressive loss of effector functions, high and sustained inhibitory receptor expression, ...Read More

Cell Adhesion Molecules ResearchGlycosylation and Glycoproteins ResearchGalectins and Cancer BiologyBiologyEffectorIntegrinCD8Lineage (genetic)ImmunologyCell biologyReceptorCell lineageCellular differentiation

MeSH terms

AnimalsCell AdhesionExtracellular MatrixHumansLeukocytesStructure-Activity RelationshipIntegrinsReceptors, Very Late Antigen
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