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Matrix Elasticity Directs Stem Cell Lineage Specification
Cell · 2006 · Vol. 126(4) · pp. 677–689
Adam J. Engler(University of Pennsylvania)Shamik Sen(University of Pennsylvania)H. Lee Sweeney(University of Pennsylvania)Dennis E. Discher✉(University of Pennsylvania)
Cellular Mechanics and Interactions3D Printing in Biomedical ResearchPluripotent Stem Cells ResearchBiologyStem cellCell biologyElasticity (physics)Matrix (chemical analysis)Cell lineageComputational biologyEvolutionary biologyCellular differentiationGenetics
MeSH terms
Cell DifferentiationCulture MediaCytoskeletonElasticityExtracellular MatrixHumansPhenotypeRNATranscription FactorsBiomarkersCell LineageOligonucleotide Array Sequence AnalysisGene Expression ProfilingFocal AdhesionsMyosin Type II
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