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A unified mixed-model method for association mapping that accounts for multiple levels of relatedness

Nature Genetics · 2005 · Vol. 38(2) · pp. 203–208
Jianming YuGaël PressoirWilliam H. BriggsI. Vroh BiMasanori YamasakiJohn DoebleyMichael D. McMullenBrandon S. GautDahlia M. NielsenJames B. HollandStephen KresovichEdward S. Buckler
Genetic Mapping and Diversity in Plants and AnimalsGenetic and phenotypic traits in livestockGenetics and Plant BreedingSpurious relationshipBiologyGenetic associationAssociation (psychology)Association mappingPopulationGeneticsType I and type II errorsQuantitative trait locusComputational biology

MeSH terms

Zea maysGenetic TechniquesHumansModels, GeneticPhenotypeResearch DesignGenetic VariationGene ExpressionQuantitative Trait, HeritableHeredity

Funding

  • National Science Foundation
  • U.S. Department of Agriculture
Citations
4,219
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30.15
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29
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References
Principles of Population Genetics.
Biometrics · 1990 · 5,349 citations
Genomic Control for Association Studies
Biometrics · 1999 · 3,224 citations
Genome-wide association studies for common diseases and complex traits
Nature Reviews Genetics · 2005 · 2,867 citations
A General Test of Association for Quantitative Traits in Nuclear Families
The American Journal of Human Genetics · 2000 · 1,145 citations
Multipoint Quantitative-Trait Linkage Analysis in General Pedigrees
The American Journal of Human Genetics · 1998 · 3,058 citations
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