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Detection and Characterization of Placental MicroRNAs in Maternal Plasma

Clinical Chemistry · 2008 · Vol. 54(3) · pp. 482–490
S ChimTristan K F ShingEmily C W HungTak-yeung LeungTze Kin LauRossa W. K. ChiuYuk Ming Dennis Lo

Abstract

We have demonstrated the existence of placental miRNAs in maternal plasma and provide some information on their stability and physical nature. These findings open up a new class of molecular markers for pregnancy monitoring.

MicroRNA in disease regulationCircular RNAs in diseasesPregnancy and preeclampsia studiesmicroRNAPlacentaPregnancyBiologyNucleic acidFetusAndrologyTaqManBlood plasmaPlacental lactogen

MeSH terms

FemaleGestational AgeHumansPlacentaPlasmaPregnancyPrenatal DiagnosisBiomarkersReverse Transcriptase Polymerase Chain ReactionMicroRNAs

Funding

  • Li Ka Shing Foundation
Citations
862
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