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PET imaging of amyloid deposition in patients with mild cognitive impairment

Neurobiology of Aging · 2007 · Vol. 29(10) · pp. 1456–1465

Anton Forsberg(Karolinska Institutet)Henry Engler(Uppsala University Hospital)Ove Almkvist(Stockholm University)Gunnar Blomquist(Uppsala University)Göran Hagman(Karolinska University Hospital)Anders WallAnna RingheimBengt Långström(Uppsala University)Agneta Nordberg✉(Karolinska University Hospital)

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Dementia and Cognitive Impairment Research Medical Imaging Techniques and Applications Alzheimer's disease research and treatmentsPittsburgh compound BPositron emission tomographyNuclear medicineStandardized uptake valueMedicineMemory clinicCognitive impairmentInternal medicineAlzheimer's diseaseEpisodic memory

MeSH terms

AgedAged, 80 and overAgingAlzheimer DiseaseAniline CompoundsCerebral CortexCognition DisordersFemaleGlucoseHumansMaleMiddle AgedNeuropsychological TestsPredictive Value of TestsPrognosis

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References

Inverse relation between in vivo amyloid imaging load and cerebrospinal fluid Aβ <sub>42</sub> in humans

Annals of Neurology · 2005 · 1,247 citations

Cerebrospinal Fluid β-Amyloid(1-42) in Alzheimer Disease

Archives of Neurology · 1999 · 667 citations

Synthesis and Evaluation of <sup>11</sup>C-Labeled 6-Substituted 2-Arylbenzothiazoles as Amyloid Imaging Agents

Journal of Medicinal Chemistry · 2003 · 977 citations

Graphical Evaluation of Blood-to-Brain Transfer Constants from Multiple-Time Uptake Data

Journal of Cerebral Blood Flow & Metabolism · 1983 · 3,589 citations

Quantification of tau phosphorylated at threonine 181 in human cerebrospinal fluid: a sandwich ELISA with a synthetic phosphopeptide for standardization

Neuroscience Letters · 2000 · 488 citations

CSF markers for incipient Alzheimer's disease

The Lancet Neurology · 2003 · 1,290 citations

Mild Cognitive Impairment Represents Early-Stage Alzheimer Disease

Archives of Neurology · 2001 · 1,853 citations

Clinical diagnosis of Alzheimer's disease

Neurology · 1984 · 27,910 citations

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