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Progression of aortic valve stenosis: TGF-β1 is present in calcified aortic valve cusps and promotes aortic valve interstitial cell calcification via apoptosis
The Annals of Thoracic Surgery · 2003 · Vol. 75(2) · pp. 457–465
Jian Bo(Children's Hospital of Philadelphia)Navneet Narula(University of Pennsylvania Health System)Quanyi Li(Children's Hospital of Philadelphia)Emile R. Mohler(University of Pennsylvania Health System)Robert J. Levy✉(Children's Hospital of Philadelphia)
Cardiac Valve Diseases and TreatmentsAortic Disease and Treatment ApproachesInfective Endocarditis Diagnosis and ManagementCalcificationAortic valveMedicineInterstitial cellAortic valve stenosisStenosisPathologyAnatomyInternal medicine
MeSH terms
AgedAged, 80 and overAlkaline PhosphataseAmino Acid Chloromethyl KetonesAnimalsAortic ValveAortic Valve StenosisCalcinosisCells, CulturedFemaleHumansImmunohistochemistryMaleSheepTransforming Growth Factor beta
Citations
432
FWCI
8.40
field-weighted impact
References
26
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98%
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Citations per year
Cited by
Calcification of Tissue Heart Valve Substitutes: Progress Toward Understanding and Prevention
The Annals of Thoracic Surgery · 2005 · 709 citations
The Emerging Role of Valve Interstitial Cell Phenotypes in Regulating Heart Valve Pathobiology
American Journal Of Pathology · 2007 · 628 citations
References
Divergence and convergence of TGF‐β/BMP signaling
Journal of Cellular Physiology · 2001 · 505 citations
Lipid Oxidation Products Have Opposite Effects on Calcifying Vascular Cell and Bone Cell Differentiation
Arteriosclerosis Thrombosis and Vascular Biology · 1997 · 616 citations
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