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Progression of aortic valve stenosis: TGF-β1 is present in calcified aortic valve cusps and promotes aortic valve interstitial cell calcification via apoptosis

The Annals of Thoracic Surgery · 2003 · Vol. 75(2) · pp. 457–465
Jian BoNavneet NarulaQuanyi LiEmile R. MohlerRobert J. Levy
Cardiac Valve Diseases and TreatmentsAortic Disease and Treatment ApproachesInfective Endocarditis Diagnosis and ManagementCalcificationAortic valveMedicineInterstitial cellAortic valve stenosisStenosisPathologyAnatomyInternal medicine

MeSH terms

AgedAged, 80 and overAlkaline PhosphataseAmino Acid Chloromethyl KetonesAnimalsAortic ValveAortic Valve StenosisCalcinosisCells, CulturedFemaleHumansImmunohistochemistryMaleSheepTransforming Growth Factor beta
Citations
432
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8.40
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26
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98%
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References
Divergence and convergence of TGF‐β/BMP signaling
Journal of Cellular Physiology · 2001 · 505 citations
Lipid Oxidation Products Have Opposite Effects on Calcifying Vascular Cell and Bone Cell Differentiation
Arteriosclerosis Thrombosis and Vascular Biology · 1997 · 616 citations
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