review Open AccessTop 10% cited
The Emerging Role of Valve Interstitial Cell Phenotypes in Regulating Heart Valve Pathobiology
American Journal Of Pathology · 2007 · Vol. 171(5) · pp. 1407–1418
Chang Amber Liu(University of Toronto)Vineet Joag(University Health Network)Avrum I. Gotlieb✉(University of Toronto)
Cardiac Valve Diseases and TreatmentsCardiac Fibrosis and RemodelingCancer-related molecular mechanisms researchPhenotypeMesenchymal stem cellFunction (biology)Heart valveFrontierInterstitial cellPathogenesisBiologyDiseaseConceptual framework
MeSH terms
AnimalsHeart Valve DiseasesHeart ValvesHumansInflammationNeovascularization, PathologicOsteoblastsTransforming Growth Factor betaNeovascularization, PhysiologicCell LineageEndothelial CellsEmbryonic Stem CellsMesenchymal Stem Cells
Funding
- Heart and Stroke Foundation of Canada
- Heart and Stroke Foundation of Canada
Citations
628
FWCI
10.87
field-weighted impact
References
117
Percentile
99%
vs. same field & year
Citations per year
References
New insights into TGF-β–Smad signalling
Trends in Biochemical Sciences · 2004 · 1,167 citations
Redefining endothelial progenitor cells via clonal analysis and hematopoietic stem/progenitor cell principals
Blood · 2006 · 1,456 citations
Progression of aortic valve stenosis: TGF-β1 is present in calcified aortic valve cusps and promotes aortic valve interstitial cell calcification via apoptosis
The Annals of Thoracic Surgery · 2003 · 432 citations
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