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Methods to improve recruitment to randomised controlled trials: Cochrane systematic review and meta-analysis

BMJ Open · 2013 · Vol. 3(2) · pp. e002360–e002360
Shaun TreweekPauline LockhartMarie PitkethlyJonathan CookMonica KjeldstrømMarit JohansenTaina TaskilaFrank SullivanSue WilsonCatherine JacksonRitu JonesElizabeth Mitchell

Abstract

There are promising strategies for increasing recruitment to trials, but some methods, such as open-trial designs and opt-out strategies, must be considered carefully as their use may also present methodological or ethical challenges. Questions remain as to the applicability of results originating from hypothetical trials, including those relating to the use of monetary incentives, and there is a clear knowledge gap with regard to effective strategies aimed at recruiters.

Health and Medical Research ImpactsEthics in Clinical ResearchDiversity and Career in MedicineMedicineMeta-analysisSystematic reviewCochrane collaborationRandomized controlled trialAlternative medicineMEDLINEInternal medicineCochrane LibraryPathology
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