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Graphene Oxide: Intrinsic Peroxidase Catalytic Activity and Its Application to Glucose Detection

Advanced Materials · 2010 · Vol. 22(19) · pp. 2206–2210
Yujun SongKonggang QuChao ZhaoJinsong RenXiaogang Qu

Abstract

Carboxyl-modified graphene oxide (GO–COOH) possesses intrinsic peroxidase-like activity that can catalyze the reaction of peroxidase substrate 3,3,5,5-tetramethylbenzidine (TMB) in the presence of H2O2 to produce a blue color reaction. A simple, cheap, and highly sensitive and selective colorimetric method for glucose detection has been developed and will facilitate the utilization of GOCOOH intrinsic peroxidase activity in medical diagnostics and biotechnology. Detailed facts of importance to specialist readers are published as ”Supporting Information”. Such documents are peer-reviewed, but not copy-edited or typeset. They are made available as submitted by the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.

Advanced Nanomaterials in CatalysisGraphene and Nanomaterials ApplicationsElectrochemical sensors and biosensorsPeroxidaseGrapheneOxideSubstrate (aquarium)CatalysisCombinatorial chemistryNanotechnologyMaterials scienceEnzymeChemistry

MeSH terms

BenzidinesCarbonGlucoseHydrogen PeroxidePeroxidaseOxidesBiocatalysis
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References
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Journal of the American Chemical Society · 2008 · 3,582 citations
The rise of graphene
Nature Materials · 2007 · 39,026 citations
Graphene-based composite materials
Nature · 2006 · 12,716 citations
A Graphene Platform for Sensing Biomolecules
Angewandte Chemie International Edition · 2009 · 2,036 citations
Processable aqueous dispersions of graphene nanosheets
Nature Nanotechnology · 2008 · 9,020 citations
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