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Risk factors for acute generalized exanthematous pustulosis (AGEP)—results of a multinational case–control study (EuroSCAR)

British Journal of Dermatology · 2007 · Vol. 157(5) · pp. 989–996

Alexis Sidoroff✉(Innsbruck Medical University)Ariane Dunant(Universität Innsbruck)Cécile Viboud(Sorbonne Université)Sima Halevy(Ben-Gurion University of the Negev)Jan Nico Bouwes Bavinck(Leiden University Medical Center)Luigi Naldi(Azienda Ospedaliero Universitaria Ospedali Riuniti)M Mockenhaupt(University of Freiburg)J.P. Fagot(Inserm)J Roujeau(Paris-Est Sup)

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Abstract

Medications associated with AGEP differ from those associated with Stevens-Johnson syndrome or toxic epidermal necrolysis. Different timing patterns from drug intake to reaction onset were observed for different drugs. Infections, although possible triggers, played no prominent role in causing AGEP and there was no evidence that AGEP is a variant of pustular psoriasis.

Drug-Induced Adverse Reactions Contact Dermatitis and Allergies Autoimmune Bullous Skin DiseasesVenereologyMedicineAcute generalized exanthematous pustulosisMultinational corporationLibrary scienceDermatologyPolitical scienceLaw

MeSH terms

TerbinafineAnti-Infective AgentsAustriaCalcium Channel BlockersDrug EruptionsDiltiazemExanthemaFemaleFranceHumansHydroxychloroquineIsraelItalyMaleMiddle Aged

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