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Drug reaction with eosinophilia and systemic symptoms (DRESS): an original multisystem adverse drug reaction. Results from the prospective RegiSCAR study
British Journal of Dermatology · 2013 · Vol. 169(5) · pp. 1071–1080
Sylvia H. Kardaun✉(University Medical Center Groningen)Peggy Sekula(University Medical Center Freiburg)L. Valeyrie‐Allanore(Université Paris-Est Créteil)Y. Liss(University Medical Center Freiburg)Chia‐Yu Chu(National Taiwan University Hospital)D. Creamer(King's College - North Carolina)Alexis Sidoroff(Innsbruck Medical University)Luigi Naldi(Centro Studi GISED)Maja Mockenhaupt(University Medical Center Freiburg)J C Roujeau(Université Paris-Est Créteil)the RegiSCAR study group
Abstract
This prospective observational study supports the hypothesis that DRESS is an original phenotype among SCAR in terms of clinical and biological characteristics, causative drugs, and time relation. The diversity of causative drugs was rather limited, and mortality was lower than that suggested by prior publications.
Drug-Induced Adverse ReactionsEosinophilic Disorders and SyndromesUrticaria and Related ConditionsMedicineEosinophiliaProspective cohort studyInterquartile rangeDermatologyAdverse drug reactionDrugLeukocytosisEtiologyInternal medicine
MeSH terms
AdultAgedDrug EruptionsFemaleHumansMaleMiddle AgedPrognosisProspective StudiesRegistriesDrug Hypersensitivity Syndrome
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References
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British Journal of Dermatology · 2007 · 913 citations
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