articleTop 1% cited

Functional bioengineered corneal epithelial sheet grafts from corneal stem cells expanded ex vivo on a temperature-responsive cell culture surface

Transplantation · 2004 · Vol. 77(3) · pp. 379–385

Kohji Nishida✉(Osaka University)Masayuki Yamato(Tokyo Women's Medical University)Yasutaka Hayashida(Osaka University)Katsuhiko WATANABE(Osaka University)Naoyuki Maeda(Osaka University)Hitoshi Watanabe(Osaka University)Kazuaki Yamamoto(Osaka University)Shigeru Nagai(Tokyo Women's Medical University)Akihiko Kikuchi(Tokyo Women's Medical University)Yasuo Tano(Osaka University)Teruo Okano(Tokyo Women's Medical University)

View via DOI Publisher page

Abstract

Cell sheet engineering technology allows us to create intact, transplantable corneal epithelial cell sheets that retain stem cells from limbal stem cells expanded ex vivo. Our research indicates highly promising clinical capabilities for our bioengineered corneal epithelial sheet.

Corneal Surgery and Treatments Ocular Surface and Contact Lens Corneal surgery and disordersEx vivoStem cellCorneal epitheliumTransplantationCorneaCell biologyTissue engineeringStromaPathologyBiology

MeSH terms

AnimalsCell DivisionCells, CulturedCytological TechniquesEyeHumansMicroscopy, ElectronPolymersPreservation, BiologicalRabbitsStem CellsSurface PropertiesOphthalmologic Surgical ProceduresTemperatureTransplantation, Heterologous

Citations

559

FWCI

25.28

field-weighted impact

References

Percentile

100%

vs. same field & year

Citations per year

Cited by

Modular tissue engineering: engineering biological tissues from the bottom up