article Open AccessTop 1% cited
Milder ovarian stimulation for in-vitro fertilization reduces aneuploidy in the human preimplantation embryo: a randomized controlled trial
Human Reproduction · 2007 · Vol. 22(4) · pp. 980–988
Esther B. Baart✉(University Medical Center Utrecht)Elena MartiniMarinus J.C. EijkemansDiane Van Opstal(Erasmus University Rotterdam)Nicole G.M. BeckersArie Verhoeff(GGD Rotterdam-Rijnmond)Nicolas S. Macklon(University Medical Center Utrecht)Bart C.J.M. Fauser(University Medical Center Utrecht)
Abstract
Future ovarian stimulation strategies should avoid maximizing oocyte yield, but aim at generating a sufficient number of chromosomally normal embryos by reduced interference with ovarian physiology.
Prenatal Screening and DiagnosticsReproductive Biology and FertilityAssisted Reproductive Technology and Twin PregnancyOocyteStimulationIn vitro fertilisationBiologyAndrologyAneuploidyEmbryoRegimenEmbryo qualityPregnancy rate
MeSH terms
AdultAneuploidyBiopsyBlastocystBlastomeresChromosomesEmbryo, MammalianFemaleFertilization in VitroHumansModels, GeneticOvulation InductionTreatment OutcomeIn Situ Hybridization, FluorescencePreimplantation Diagnosis
Funding
- Erasmus+
Citations
610
FWCI
51.46
field-weighted impact
References
57
Percentile
100%
vs. same field & year
Citations per year
References
To err (meiotically) is human: the genesis of human aneuploidy
Nature Reviews Genetics · 2001 · 2,482 citations
ESHRE PGD Consortium data collection XIII: cycles from January to December 2010 with pregnancy follow-up to October 2011
Human Reproduction · 2015 · 707 citations
Comparison of blastocyst transfer with or without preimplantation genetic diagnosis for aneuploidy screening in couples with advanced maternal age: a prospective randomized controlled trial
Human Reproduction · 2004 · 568 citations
Group sequential methods in the design and analysis of clinical trials
Biometrika · 1977 · 1,771 citations
Oocyte control of ovarian follicular development and function in mammals
Reproduction · 2001 · 980 citations
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