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Comparison of blastocyst transfer with or without preimplantation genetic diagnosis for aneuploidy screening in couples with advanced maternal age: a prospective randomized controlled trial

Human Reproduction · 2004 · Vol. 19(12) · pp. 2849–2858
C. StaessenPeter PlatteauElvire Van AsscheAn MichielsHerman TournayeMichel CamusPaul DevroeyInge LiebaersAndré Van Steirteghem

Abstract

This RCT provides no arguments in favour of PGD-AS for improving clinical outcome per initiated cycle in patients with AMA when there are no restrictions in the number of embryos to be transferred.

Prenatal Screening and DiagnosticsAssisted Reproductive Technology and Twin PregnancyCongenital Anomalies and Fetal SurgeryAneuploidyBlastocyst TransferAdvanced maternal ageRandomized controlled trialMedicineObstetricsGynecologyBlastocystPregnancyBiology

MeSH terms

AdultAneuploidyBlastocystEmbryo TransferFemaleHumansMaleMaternal AgePregnancyPregnancy OutcomeProspective StudiesIn Situ Hybridization, FluorescencePreimplantation Diagnosis

Funding

  • Fonds Wetenschappelijk Onderzoek
  • Vlaamse regering
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