articleTop 1% cited

G-CSF induces stem cell mobilization by decreasing bone marrow SDF-1 and up-regulating CXCR4

Nature Immunology · 2002 · Vol. 3(7) · pp. 687–694

Isabelle Petit✉(Weizmann Institute of Science)Martine Szyper‐Kravitz(Meir Medical Center)Arnon Nagler(Sheba Medical Center)Meir Lahav(Meir Medical Center)Amnon Peled(Hadassah Academic College)Liliana Habler(Assaf Harofeh Medical Center)Tanya Ponomaryov(Weizmann Institute of Science)Russell S. Taichman(University of Michigan–Ann Arbor)Fernando Arenzana‐Seisdedos(Institut Pasteur)Nobutaka Fujii(Kyoto Pharmaceutical University)Judith Sandbank(Assaf Harofeh Medical Center)Dov Zipori(Weizmann Institute of Science)Tsvee Lapidot(Weizmann Institute of Science)

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Hematopoietic Stem Cell Transplantation Chemokine receptors and signaling Immune Response and InflammationCXCR4Stem cellStromal cellStromal cell-derived factor 1HaematopoiesisProgenitor cellGranulocyte colony-stimulating factorBone marrowNeutrophil elastaseStem cell factor

MeSH terms

AnimalsBone MarrowBone Marrow CellsCell LineCell MovementHematopoietic Stem CellsHumansLymphomaMice, Inbred BALB COsteoblastsPancreatic ElastaseRNA, MessengerUp-RegulationGene ExpressionGranulocyte Colony-Stimulating Factor

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