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The role of iron in brain ageing and neurodegenerative disorders

The Lancet Neurology · 2014 · Vol. 13(10) · pp. 1045–1060

Roberta J. Ward(Imperial College London)Fabio A. Zucca(National Research Council)Jeff H. Duyn(National Institute of Neurological Disorders and Stroke)Robert R. Crichton(UCLouvain)Luigi Zecca✉(Institute of Biomedical Technologies)

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Neurological diseases and metabolism Iron Metabolism and Disorders Neurological and metabolic disordersAgeingNeurosciencePsychologyMedicineInternal medicine

MeSH terms

AgingAnimalsBrainBrain ChemistryHumansIronIron Chelating AgentsMagnetic Resonance ImagingBiomarkersNeuroprotective AgentsNonheme Iron ProteinsNeurodegenerative Diseases

Funding

Ministero dell’Istruzione, dell’Università e della Ricerca
Consiglio Nazionale delle Ricerche

Citations

1,764

FWCI

37.95

field-weighted impact

References

235

Percentile

100%

vs. same field & year

Citations per year

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References

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THE EFFECT OF AGE ON THE NON‐HAEMIN IRON IN THE HUMAN BRAIN

Journal of Neurochemistry · 1958 · 1,434 citations

Friedreich's ataxia: Pathology, pathogenesis, and molecular genetics

Journal of the Neurological Sciences · 2011 · 439 citations

Increased Nigral Iron Content and Alterations in Other Metal Ions Occurring in Brain in Parkinson's Disease

Journal of Neurochemistry · 1989 · 1,141 citations

Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death

Cell · 2012 · 17,296 citations

Microglia-mediated neurotoxicity: uncovering the molecular mechanisms

Nature reviews. Neuroscience · 2006 · 4,065 citations

Astrocyte–endothelial interactions at the blood–brain barrier

Nature reviews. Neuroscience · 2005 · 5,452 citations

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