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Nivolumab versus chemotherapy in patients with advanced melanoma who progressed after anti-CTLA-4 treatment (CheckMate 037): a randomised, controlled, open-label, phase 3 trial

The Lancet Oncology · 2015 · Vol. 16(4) · pp. 375–384
Jeffrey S. WeberSandra P. D’AngeloDavid R. MinorF. Stephen HodiRalf GutzmerBart NeynsChristoph HöellerNikhil I. KhushalaniWilson H. MillerChristopher D. LaoGerald P. LinetteL. ThomasPaul LoriganKenneth F. GrossmannJessica C. HasselMichele MaioMario SznolPaolo A. AsciertoPeter MohrBartosz ChmielowskiAlan H. BryceInge Marie SvaneJean‐Jacques GrobAngela M. KrackhardtChristine E. HorakAlexandre LambertArvin YangJames Larkin
Cancer Immunotherapy and BiomarkersCAR-T cell therapy researchImmunotherapy and Immune ResponsesOpen labelMedicineNivolumabOncologyChemotherapyInternal medicineIpilimumabRandomized controlled trialImmunotherapyCancer

MeSH terms

CarboplatinIpilimumabNivolumabAdultAgedAged, 80 and overAntibodies, MonoclonalAntineoplastic Combined Chemotherapy ProtocolsFemaleHumansMaleMelanomaMiddle AgedNeoplasm StagingPaclitaxel

Funding

  • GlaxoSmithKline
  • NIHR Biomedical Research Centre, Royal Marsden NHS Foundation Trust/Institute of Cancer Research
  • National Institute for Health and Care Research
  • National Institutes of Health
Citations
2,648
FWCI
167.40
field-weighted impact
References
36
Percentile
100%
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