article Open AccessTop 10% cited
Development of Lupus-like Autoimmune Diseases by Disruption of the PD-1 Gene Encoding an ITIM Motif-Carrying Immunoreceptor
Immunity · 1999 · Vol. 11(2) · pp. 141–151
Hiroyuki Nishimura✉(Kyoto University)Masato Nose(Ehime University)Hiroshi Hiai(Kyoto University)Nagahiro Minato(Kyoto University)Tasuku Honjo(Kyoto University)
T-cell and B-cell ImmunologyImmune Cell Function and InteractionImmunotherapy and Immune ResponsesBiologyGeneSystemic lupus erythematosusGeneticsComputational biologyImmunologyDiseaseInternal medicineMedicine
MeSH terms
AnimalsAntigens, SurfaceArthritis, RheumatoidH-2 AntigensImmune ToleranceGenetic LinkageLupus NephritisLymphocyte ActivationMice, Inbred BALB CMice, TransgenicProteinsT-LymphocytesMice, Inbred MRL lprApoptosis Regulatory ProteinsMice
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References
Induced expression of PD-1, a novel member of the immunoglobulin gene superfamily, upon programmed cell death.
The EMBO Journal · 1992 · 3,162 citations
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