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APOE and Alzheimer disease: a major gene with semi-dominant inheritance

Molecular Psychiatry · 2011 · Vol. 16(9) · pp. 903–907

Emmanuelle Génin(Inserm)Didier Hannequin(Inserm)David Wallon(Inserm)Kristel Sleegers(University of Antwerp)Mikko Hiltunen(Kuopio University Hospital)Onofre Combarros(Centro de Investigación Biomédica en Red)María J. Bullido(Centro de Biología Molecular Severo Ochoa)Sebastiaan Engelborghs(ZNA Middelheim Hospital)Peter Paul De Deyn(University of Antwerp)Claudine Berr(Université de Montpellier)Florence Pasquier(Lille’s Cardiology Hospital)Bruno Dubois(Sorbonne Université)Gloria Tognoni(University of Pisa)Nathalie Fiévet(Inserm)Nathalie Brouwers(VIB-UAntwerp Center for Molecular Neurology)Karolien Bettens(University of Antwerp)Beatrice Arosio(University of Milan)Eliécer Coto(Hospital Universitario Central de Asturias)Maria Del Zompo(University of Cagliari)Ignacio Mateo(Universidad de Cantabria)Jacques Epelbaum(Université Paris Cité)Ana Frank(Universidad Autónoma de Madrid)Seppo Helisalmi(University of Eastern Finland)Elisa Porcellini(University of Bologna)Alberto Pilotto(Casa Sollievo della Sofferenza)Paola Forti(IRCCS Azienda Ospedliero-Universitaria di Bologna Policlinico di Sant'Orsola)Raffaele Ferri(Oasi Maria SS)Elio Scarpini(Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico)Gabriele Siciliano(University of Pisa)Vincenzo Solfrizzi(University of Bari Aldo Moro)Sandro Sorbi(University of Florence)Gianfranco Spalletta(Fondazione Santa Lucia)Fernando Valdivieso(Universidad Autónoma de Madrid)Saila Vepsäläinen(University of Eastern Finland)Victoria Álvarez(Hospital Universitario Central de Asturias)Paolo Bosco(Oasi Maria SS)Michelangelo Mancuso(University of Pisa)Francesco Panza(University of Bari Aldo Moro)Benedetta Nacmias(University of Florence)Paola Bossù(Fondazione Santa Lucia)Olivier Hanon(Université Paris Cité)Paola Piccardi(University of Cagliari)G Annoni(University of Milano-Bicocca)Davide Seripa(Istituti di Ricovero e Cura a Carattere Scientifico)Daniela Galimberti(University of Milan)Federico Licastro(University of Bologna)Hilkka Soininen(University of Eastern Finland)Dartigues Jf(Inserm)M. Ilyas Kamboh(University of Pittsburgh)Christine Van Broeckhoven(University of Antwerp)Jean‐Charles Lambert(Centre Hospitalier Universitaire de Lille)Philippe Amouyel(Centre Hospitalier Universitaire de Lille)Dominique Campion✉(Inserm)

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Alzheimer's disease research and treatments Genetic Associations and Epidemiology Amyloidosis: Diagnosis, Treatment, OutcomesApolipoprotein EMendelian inheritanceDementiaDiseaseAlleleOdds ratioRisk factorGenotypeAge of onsetGenetics

MeSH terms

Age FactorsAgedAllelesAlzheimer DiseaseFemaleFranceGenotypeHumansMaleMiddle AgedUnited StatesIncidenceOdds RatioCase-Control StudiesGenetic Predisposition to Disease

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