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A New Era for Cancer Treatment: Gold‐Nanoparticle‐Mediated Thermal Therapies

Small · 2010 · Vol. 7(2) · pp. 169–183
Laura C. KennedyLissett R. BickfordNastassja A. LewinskiAndrew J. CoughlinYing HuEmily S. DayJennifer L. WestRebekah A. Drezek

Abstract

Nanotechnology-based cancer treatment approaches potentially provide localized, targeted therapies that aim to enhance efficacy, reduce side effects, and improve patient quality of life. Gold-nanoparticle-mediated hyperthermia shows particular promise in animal studies, and early clinical testing is currently underway. In this article, the rapidly evolving field of gold nanoparticle thermal therapy is reviewed, highlighting recent literature and describing current challenges to clinical translation of the technology.

Nanoparticle-Based Drug DeliveryNanoplatforms for cancer theranosticsGold and Silver Nanoparticles Synthesis and ApplicationsNanotechnologyColloidal goldCancer therapyCancer treatmentCancerNanoparticleMedicineMaterials scienceIntensive care medicineInternal medicine

MeSH terms

GoldHumansHyperthermia, InducedNeoplasmsNanotechnologyMetal Nanoparticles
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Toxicology and Applied Pharmacology · 2009 · 645 citations
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