reviewTop 1% cited

Effect of pegylation on pharmaceuticals

Nature Reviews Drug Discovery · 2003 · Vol. 2(3) · pp. 214–221

J. Milton Harris✉(Nektar Therapeutics (United States))Robert B. Chess(Nektar Therapeutics (United States))

Hepatitis B Virus Studies Hepatitis C virus research Peptidase Inhibition and AnalysisPEGylationClearancePolyethylene glycolPeptideChemistryProteolytic enzymesPharmacologyPEG ratioBiopharmaceuticalEnzyme

MeSH terms

AnimalsChemistry, PharmaceuticalClinical Trials as TopicPharmaceutical PreparationsHumansPharmaceutic AidsPharmacokineticsPolyethylene GlycolsHydrogels

Citations

3,358

FWCI

34.54

field-weighted impact

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100%

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References

Polyethylenglykol-umhülltes (pegyliertes) liposomales Doxorubicin

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Journal of Pharmaceutical Sciences · 1994 · 729 citations

Peginterferon Alfa-2a plus Ribavirin for Chronic Hepatitis C Virus Infection

New England Journal of Medicine · 2002 · 6,389 citations

Chemistry for peptide and protein PEGylation

Advanced Drug Delivery Reviews · 2002 · 1,594 citations

Peginterferon alfa-2b plus ribavirin compared with interferon alfa-2b plus ribavirin for initial treatment of chronic hepatitis C: a randomised trial

The Lancet · 2001 · 6,046 citations

Pegylated interferon-α2b: Pharmacokinetics, pharmacodynamics, safety, and preliminary efficacy data

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