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Statistics review 4: sample size calculations.

Critical Care · 2002 · Vol. 6(4) · pp. 335–335
Elise WhitleyJonathan Ball

Abstract

The present review introduces the notion of statistical power and the hazard of under-powered studies. The problem of how to calculate an ideal sample size is also discussed within the context of factors that affect power, and specific methods for the calculation of sample size are presented for two common scenarios, along with extensions to the simplest case.

Healthcare Technology and Patient MonitoringSepsis Diagnosis and TreatmentHeart Rate Variability and Autonomic ControlSample size determinationMedicineStatisticsContext (archaeology)Sample (material)Statistical powerIdeal (ethics)EconometricsMathematicsEpistemology

MeSH terms

Clinical Trials as TopicHumansResearch DesignRespiratory Distress SyndromeShock, SepticStatistics as TopicSample Size
Citations
582
FWCI
2.62
field-weighted impact
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14
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90%
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Citations per year
References
Early Goal-Directed Therapy in the Treatment of Severe Sepsis and Septic Shock
New England Journal of Medicine · 2001 · 10,728 citations
Practical Statistics for Medical Research.
Biometrics · 1992 · 11,721 citations
Practical Statistics for Medical Research.
Journal of the American Statistical Association · 1992 · 4,865 citations
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