articleTop 1% cited
Pharmacological profile of the α4β2 nicotinic acetylcholine receptor partial agonist varenicline, an effective smoking cessation aid
Neuropharmacology · 2006 · Vol. 52(3) · pp. 985–994
Hans Rollema✉(Pfizer (United States))Leslie K. Chambers(Pfizer (United States))J.W. Coe(Pfizer (United States))John R. Glowa(Pfizer (United States))Raymond S Hurst(Pfizer (United States))Lorraine A. Lebel(Pfizer (United States))Yi Lu(Pfizer (United States))Robert S. Mansbach(Pfizer (United States))Robert J. Mather(Pfizer (United States))Charles C. Rovetti(Pfizer (United States))Steven B. Sands(Pfizer (United States))Eric Schaeffer(Pfizer (United States))David W. Schulz(Pfizer (United States))F. David Tingley(Pfizer (United States))Kathryn Williams(Pfizer (United States))
Nicotinic Acetylcholine Receptors StudySmoking Behavior and CessationReceptor Mechanisms and SignalingVareniclinePartial agonistPharmacologyNicotineNicotinic agonistSmoking cessationAgonistNicotinic acetylcholine receptorDopamineNucleus accumbens
MeSH terms
VareniclineAnimalsBehavior, AnimalBenzazepinesBrainCell Line, TransformedDopamineDose-Response Relationship, DrugDrug Administration ScheduleHumansMaleMembrane PotentialsNicotineProtein BindingQuinoxalines
Funding
- Pfizer
Citations
533
FWCI
13.71
field-weighted impact
References
44
Percentile
99%
vs. same field & year
Citations per year
Cited by
Varenicline: An α4β2 Nicotinic Receptor Partial Agonist for Smoking Cessation
Journal of Medicinal Chemistry · 2005 · 930 citations
References
Varenicline: An α4β2 Nicotinic Receptor Partial Agonist for Smoking Cessation
Journal of Medicinal Chemistry · 2005 · 930 citations
Nicotine maintains robust self-administration in rats on a limited-access schedule
Psychopharmacology · 1989 · 587 citations
Neural systems of reinforcement for drug addiction: from actions to habits to compulsion
Nature Neuroscience · 2005 · 3,760 citations
Mortality in relation to smoking: 40 years' observations on male British doctors
BMJ · 1994 · 5,770 citations
Varenicline Is a Partial Agonist at α4β2 and a Full Agonist at α7 Neuronal Nicotinic Receptors
Molecular Pharmacology · 2006 · 552 citations
Mortality in relation to smoking: 50 years' observations on male British doctors
BMJ · 2004 · 2,902 citations
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