articleTop 1% cited

Diverse Roles of the Nuclear Orphan Receptor CAR in Regulating Hepatic Genes in Response to Phenobarbital

Molecular Pharmacology · 2002 · Vol. 61(1) · pp. 1–6

Akiko Ueda✉(National Institute of Environmental Health Sciences)Hisham K. Hamadeh(National Institute of Environmental Health Sciences)Heather K. Webb(National Institute of Environmental Health Sciences)Yukio Yamamoto(National Institute of Environmental Health Sciences)Tatsuya Sueyoshi(National Institute of Environmental Health Sciences)Cynthia A. Afshari(National Institute of Environmental Health Sciences)Jürgen M. Lehmann(National Institutes of Health)Masahiko Negishi(National Institutes of Health)

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Nuclear Receptors and Signaling Pharmacogenetics and Drug Metabolism Estrogen and related hormone effectsConstitutive androstane receptorGeneBiologyPregnane X receptorTranscription factorNuclear receptorPsychological repressionCytochrome P450Aldehyde dehydrogenaseEnzyme

MeSH terms

Constitutive Androstane ReceptorAnimalsAnticonvulsantsCytochrome P-450 Enzyme SystemFemaleGene Expression RegulationMalePhenobarbitalTranscription FactorsReceptors, Cytoplasmic and NuclearReverse Transcriptase Polymerase Chain ReactionOligonucleotide Array Sequence AnalysisHepatocytesMice

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466

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12.65

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