articleTop 1% cited
Initiation of Inappropriate Antimicrobial Therapy Results in a Fivefold Reduction of Survival in Human Septic Shock
CHEST Journal · 2009 · Vol. 136(5) · pp. 1237–1248
Anand Kumar(St. Boniface Hospital)Anand Kumar✉(University Health Network)Peter Ellis(University Health Network)Yaseen M. Arabi(King Saud bin Abdulaziz University for Health Sciences)Dan Roberts(St. Boniface Hospital)Bruce Light(St. Boniface Hospital)Joseph E. Parrillo(University of British Columbia)Peter Dodek(Island Health)Gordon Wood(Island Health)Aseem Kumar(Rush University Medical Center)Aseem Kumar✉(St. Boniface Hospital)David Simón(Rush University Medical Center)Cheryl Peters(St. Boniface Hospital)Muhammad Ahsan(St. Boniface Hospital)Dan Château(University of Manitoba)
Sepsis Diagnosis and TreatmentAntibiotic Use and ResistanceBacterial Identification and Susceptibility TestingMedicineAntimicrobialSeptic shockBacteremiaInternal medicineOdds ratioIntensive care medicineMortality rateSepsisSurgery
MeSH terms
Anti-Bacterial AgentsHumansRetrospective StudiesShock, SepticComorbiditySurvival RateOdds Ratio
Citations
1,171
FWCI
28.91
field-weighted impact
References
49
Percentile
100%
vs. same field & year
Citations per year
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References
Duration of hypotension before initiation of effective antimicrobial therapy is the critical determinant of survival in human septic shock*
Critical Care Medicine · 2006 · 6,021 citations
APACHE II-A Severity of Disease Classification System
Critical Care Medicine · 1986 · 13,403 citations
Bloodstream Infections Caused by Antibiotic-Resistant Gram-Negative Bacilli: Risk Factors for Mortality and Impact of Inappropriate Initial Antimicrobial Therapy on Outcome
Antimicrobial Agents and Chemotherapy · 2005 · 691 citations
The Influence of Inadequate Antimicrobial Treatment of Bloodstream Infections on Patient Outcomes in the ICU Setting
CHEST Journal · 2000 · 1,794 citations
Inadequate Antimicrobial Treatment of Infections
CHEST Journal · 1999 · 1,816 citations
Gram-negative bacteremia
The American Journal of Medicine · 1980 · 1,332 citations
Definitions for Sepsis and Organ Failure and Guidelines for the Use of Innovative Therapies in Sepsis
CHEST Journal · 1992 · 13,160 citations
APACHE II
Critical Care Medicine · 1985 · 13,529 citations
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