articleTop 10% cited

Accelerated Blood Clearance and Altered Biodistribution of Repeated Injections of Sterically Stabilized Liposomes

Journal of Pharmacology and Experimental Therapeutics · 2000 · Vol. 292(3) · pp. 1071–1079

E.T.M. Dams✉(Radboud University Nijmegen)Peter LavermanWim J.G. OyenGert StormGerrit L. ScherphofJ.W.M. van der MeerFrans H.M. CorstensOtto C. Boerman

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Nanoparticle-Based Drug Delivery RNA Interference and Gene Delivery Drug Transport and Resistance MechanismsBiodistributionLiposomePharmacokineticsPharmacologyChemistryPEG ratioDrug carrierDistribution (mathematics)ToxicitySpleen

MeSH terms

AnimalsComplement System ProteinsDrug CarriersFemaleInjectionsLiposomesLiverMacaca mulattaMaleMetabolic Clearance RatePolyethylene GlycolsSpecies SpecificityTissue DistributionRats, WistarMice

Citations

581

FWCI

5.29

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96%

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References

Protein and cell membrane iodinations with a sparingly soluble chloroamide, 1,3,4,6-tetrachloro-3a,6a-diphenylglycoluril

Biochemical and Biophysical Research Communications · 1978 · 4,594 citations

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