review Open AccessTop 1% cited

Designing antimicrobial peptides: form follows function

Nature Reviews Drug Discovery · 2011 · Vol. 11(1) · pp. 37–51

Christopher D. Fjell✉(University of British Columbia)Jan A. Hiss(ETH Zurich)Robert E. W. Hancock(University of British Columbia)Gisbert Schneider(ETH Zurich)

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Antimicrobial Peptides and Activities Biochemical and Structural Characterization vaccines and immunoinformatics approachesAntimicrobialAntibioticsAntimicrobial peptidesAntibiotic resistanceComputational biologyFunction (biology)BiologyBroad spectrumMicrobiologyCombinatorial chemistry

MeSH terms

Amino Acid SequenceAnimalsAnti-Bacterial AgentsClinical Trials as TopicHumansMolecular Sequence DataDrug DesignAntimicrobial Cationic PeptidesDrug Resistance, Multiple, Bacterial

Funding

National Science Foundation
Deutsche Forschungsgemeinschaft
Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung
Canadian Institutes of Health Research

Citations

1,976

FWCI

53.60

field-weighted impact

References

222

Percentile

100%

vs. same field & year

Citations per year

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References

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Nature Reviews Microbiology · 2005 · 5,673 citations

Antimicrobial and host-defense peptides as new anti-infective therapeutic strategies

Nature Biotechnology · 2006 · 4,069 citations

Diversity of antimicrobial peptides and their mechanisms of action

Biochimica et Biophysica Acta (BBA) - Biomembranes · 1999 · 1,353 citations

Control of cell selectivity of antimicrobial peptides

Biochimica et Biophysica Acta (BBA) - Biomembranes · 2008 · 689 citations

Hierarchical Grouping to Optimize an Objective Function

Journal of the American Statistical Association · 1963 · 18,957 citations

Multifunctional cationic host defence peptides and their clinical applications

Cellular and Molecular Life Sciences · 2011 · 591 citations

The role of antibiotics and antibiotic resistance in nature

Environmental Microbiology · 2009 · 676 citations

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