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An expanded genome-scale model of Escherichia coli K-12 (iJR904 GSM/GPR)

Genome biology · 2003 · Vol. 4(9) · pp. R54–R54

Jennifer L. Reed✉(University of California, San Diego)Thuy D. Vo(University of California, Los Angeles)Christophe H. Schilling(Genomatica (United States))Bernhard Ø. Palsson(University of California, Los Angeles)

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Abstract

E. coli iJR904 has improved capabilities over iJE660a. iJR904 is a more complete and chemically accurate description of E. coli metabolism than iJE660a. Perhaps most importantly, iJR904 can be used for analyzing and integrating the diverse datasets. iJR904 will help to outline the genotype-phenotype relationship for E. coli K-12, as it can account for genomic, transcriptomic, proteomic and fluxomic data simultaneously.

Microbial Metabolic Engineering and Bioproduction Biofuel production and bioconversion Protein Structure and DynamicsBiologyEscherichia coliORFSIn silicoComputational biologyFlux balance analysisGenomeSystems biologyGeneticsModel organism

MeSH terms

Citric Acid CycleEscherichia coliGenes, BacterialGlycerolKetoglutaric AcidsModels, BiologicalOpen Reading FramesGenome, BacterialEscherichia coli Proteins