reviewTop 1% cited
Drug targeting to tumors: Principles, pitfalls and (pre-) clinical progress
Journal of Controlled Release · 2011 · Vol. 161(2) · pp. 175–187
Twan Lammers✉(RWTH Aachen University)Fabian Kießling(RWTH Aachen University)Wim E. Hennink(Utrecht University)Gert Storm(Utrecht University)
Nanoparticle-Based Drug DeliveryNanoplatforms for cancer theranosticsRNA Interference and Gene DeliveryNanomedicineDrugMedicineDrug deliveryTargeted drug deliveryPharmacologyNanotechnologyNanoparticle
MeSH terms
AnimalsAntineoplastic AgentsDrug Evaluation, PreclinicalHumansNeoplasmsDrug Delivery Systems
Funding
- European Commission
- Deutsche Forschungsgemeinschaft
Citations
1,274
FWCI
37.95
field-weighted impact
References
105
Percentile
100%
vs. same field & year
Citations per year
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References
Tumor vascular permeability and the EPR effect in macromolecular therapeutics: a review
Journal of Controlled Release · 2000 · 6,447 citations
High interstitial fluid pressure — an obstacle in cancer therapy
Nature reviews. Cancer · 2004 · 2,134 citations
Nanocarriers as an emerging platform for cancer therapy
Nature Nanotechnology · 2007 · 8,478 citations
The Hallmarks of Cancer
Cell · 2000 · 28,385 citations
Targeted drug delivery to tumors: Myths, reality and possibility
Journal of Controlled Release · 2011 · 1,886 citations
Nanoparticle therapeutics: an emerging treatment modality for cancer
Nature Reviews Drug Discovery · 2008 · 4,194 citations
Reduced cardiotoxicity and comparable efficacy in a phase IIItrial of pegylated liposomal doxorubicin HCl(CAELYX™/Doxil®) versus conventional doxorubicin forfirst-line treatment of metastatic breast cancer
Annals of Oncology · 2004 · 1,701 citations
Polymeric Micelles in Anticancer Therapy: Targeting, Imaging and Triggered Release
Pharmaceutical Research · 2010 · 925 citations
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