articleTop 10% cited

Effects of obstructive sleep apnea on endothelin-1 and blood pressure

Journal of Hypertension · 1999 · Vol. 17(1) · pp. 61–66

Bradley G. Phillips(University of Iowa)Krzysztof Narkiewicz(University of Iowa)Catherine A. Pesek(University of Iowa)William G. Haynes(University of Iowa)Mark Eric DykenVirend K. Somers✉(University of Iowa)

View via DOI Publisher page

Abstract

Sleep apnea elicits increases in blood pressure and endothelin-1, with reductions in both after treatment. Vasoconstrictor and mitogenic effects of endothelin-1 may be implicated in increased cardiovascular risk in patients with obstructive sleep apnea.

Obstructive Sleep Apnea Research Neuroscience of respiration and sleep Nitric Oxide and Endothelin EffectsMedicineObstructive sleep apneaBlood pressureContinuous positive airway pressurePlasma renin activityEndothelin receptorApneaInternal medicineAnesthesiaSleep apnea

MeSH terms

Angiotensin IBlood Gas AnalysisBlood PressureCatecholaminesFemaleFollow-Up StudiesHumansMaleMiddle AgedPositive-Pressure RespirationProspective StudiesRadioimmunoassayRecurrenceReninSleep Apnea Syndromes

Citations

456

FWCI

4.26

field-weighted impact

References

Percentile

95%

vs. same field & year

Citations per year

Cited by

Pathophysiology of Sleep Apnea