article Open AccessTop 10% cited
Motor deficits, neuron loss, and reduced anxiety coinciding with axonal degeneration and intraneuronal Aβ aggregation in the 5XFAD mouse model of Alzheimer's disease
Neurobiology of Aging · 2010 · Vol. 33(1) · pp. 196.e29–196.e40
Sadim Jawhar(University of Göttingen)Anna Trawicka(University of Göttingen)Carolin Jenneckens(University of Göttingen)Thomas A. Bayer(University of Göttingen)Oliver Wirths✉(University of Göttingen)
Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration MechanismsNeuroscience and Neuropharmacology ResearchNeuroscienceHippocampusNeuronPsychologyPhenotypeExtracellularSpinal cordMotor cortexBiologyCell biology
MeSH terms
AgingAlzheimer DiseaseAnimalsAnxietyAxonsCentral Nervous SystemDisease Models, AnimalMaleMemory, Short-TermMice, Inbred C57BLMice, TransgenicNerve DegenerationNeuronsPsychomotor PerformanceAmyloid beta-Peptides
Funding
- European Commission
Citations
599
FWCI
8.89
field-weighted impact
References
69
Percentile
98%
vs. same field & year
Citations per year
References
Triple-Transgenic Model of Alzheimer's Disease with Plaques and Tangles
Neuron · 2003 · 4,102 citations
Design-based stereology in neuroscience
Neuroscience · 2004 · 688 citations
Intraneuronal Alzheimer Aβ42 Accumulates in Multivesicular Bodies and Is Associated with Synaptic Pathology
American Journal Of Pathology · 2002 · 704 citations
Intraneuronal Aβ42 Accumulation in Human Brain
American Journal Of Pathology · 2000 · 989 citations
Classification and basic pathology of Alzheimer disease
Acta Neuropathologica · 2009 · 1,011 citations
Intraneuronal β-Amyloid Aggregates, Neurodegeneration, and Neuron Loss in Transgenic Mice with Five Familial Alzheimer's Disease Mutations: Potential Factors in Amyloid Plaque Formation
Journal of Neuroscience · 2006 · 3,502 citations
Citation Network
How this paper connects to the literature. Drag to explore, click any node to open that paper.