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Intraneuronal Alzheimer Aβ42 Accumulates in Multivesicular Bodies and Is Associated with Synaptic Pathology

American Journal Of Pathology · 2002 · Vol. 161(5) · pp. 1869–1879
Reisuke H. TakahashiTeresa A. MilnerFeng LiEllen E. NamMark EdgarHaruyasu YamaguchiM. Flint BealHuaxi XuPaul GreengardGunnar K. Gouras
Alzheimer's disease research and treatmentsDementia and Cognitive Impairment ResearchPrion Diseases and Protein MisfoldingGenetically modified mouseAmyloid (mycology)Amyloid betaBACE1-ASPathologyNeuropathologyAlzheimer's diseaseNeuroscienceIntracellularNeurodegeneration

MeSH terms

AgingAlzheimer DiseaseAnimalsBrainHumansMice, TransgenicMiddle AgedNeuronsPeptide FragmentsSynapsesAmyloid beta-PeptidesMicroscopy, ImmunoelectronAmyloid beta-Protein PrecursorMice, KnockoutCytoplasmic Vesicles

Funding

  • Alzheimer's Association
  • American Academy of Neurology
  • National Institutes of Health
Citations
704
FWCI
11.87
field-weighted impact
References
74
Percentile
99%
vs. same field & year
Citations per year
References
Intraneuronal Aβ42 Accumulation in Human Brain
American Journal Of Pathology · 2000 · 989 citations
The Fine Structure of the Nervous System.
Archives of Neurology · 1970 · 1,954 citations
Membrane transport in the endocytic pathway
Current Opinion in Cell Biology · 1995 · 641 citations
Alzheimer's Disease: Genes, Proteins, and Therapy
Physiological Reviews · 2001 · 6,050 citations
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