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Glutamine addiction: a new therapeutic target in cancer

Trends in Biochemical Sciences · 2010 · Vol. 35(8) · pp. 427–433
David R. WiseCraig B. Thompson
Cancer, Hypoxia, and MetabolismAmino Acid Enzymes and MetabolismMetabolism, Diabetes, and CancerGlutamineAmino acidBiochemistryCancer cellBiosynthesisBiologyMitochondrionMetabolismNucleotideAmino acid synthesis

MeSH terms

AnimalsGlutamineHumansMitochondriaNADPNeoplasmsNucleotidesProtein BiosynthesisTOR Serine-Threonine KinasesMolecular Targeted Therapy
Citations
1,747
FWCI
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References
THE METABOLISM OF TUMORS
The American Journal of the Medical Sciences · 1931 · 813 citations
Targeting the phosphoinositide 3-kinase pathway in cancer
Nature Reviews Drug Discovery · 2009 · 2,742 citations
Tumor Cell Metabolism: Cancer's Achilles' Heel
Cancer Cell · 2008 · 2,271 citations
On the Origin of Cancer Cells
Science · 1956 · 13,149 citations
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