article Open AccessTop 1% cited
Inhibitors of Class 1 Histone Deacetylases Reverse Contextual Memory Deficits in a Mouse Model of Alzheimer's Disease
Neuropsychopharmacology · 2009 · Vol. 35(4) · pp. 870–880
Mark Kilgore✉(University of Alabama at Birmingham)Courtney A. Miller(University of Alabama at Birmingham)Daniel M. Fass(Massachusetts Institute of Technology)Krista M. Hennig(Center for Human Genetics)Stephen J. Haggarty(Center for Human Genetics)J. David Sweatt(University of Alabama at Birmingham)Gavin Rumbaugh(University of Alabama at Birmingham)
Histone Deacetylase Inhibitors ResearchAlzheimer's disease research and treatmentsCholinesterase and Neurodegenerative DiseasesSodium butyrateVorinostatHistone deacetylase inhibitorHDAC6Genetically modified mousePharmacologyHistone deacetylaseAlzheimer's diseaseDementiaPsychology
MeSH terms
Alzheimer DiseaseAnalysis of VarianceAnimalsConditioning, ClassicalDisease Models, AnimalEnzyme InhibitorsFearFemaleHippocampusHumansMaleMemory DisordersMice, Inbred C57BLMice, TransgenicAmyloid beta-Protein Precursor
Funding
- Brain Research Foundation
- American Health Assistance Foundation
- McKnight Foundation
- Evelyn F. McKnight Brain Research Foundation
- Stanley Medical Research Institute
- National Alliance for Research on Schizophrenia and Depression
- National Institute of Mental Health
- National Institute of Neurological Disorders and Stroke
Citations
721
FWCI
17.48
field-weighted impact
References
49
Percentile
100%
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Citations per year
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Cell · 2007 · 10,677 citations
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Annual Review of Neuroscience · 2004 · 2,663 citations
Mutant presenilins specifically elevate the levels of the 42 residue β-amyloid peptide in vivo: evidence for augmentation of a 42-specific γ secretase
Human Molecular Genetics · 2003 · 1,581 citations
Translating the Histone Code
Science · 2001 · 9,632 citations
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