reviewTop 1% cited
The ubiquitin-proteasome pathway: on protein death and cell life
The EMBO Journal · 1998 · Vol. 17(24) · pp. 7151–7160
Aaron Ciechanover✉(Technion – Israel Institute of Technology)
Ubiquitin and proteasome pathwaysAutophagy in Disease and TherapyEndoplasmic Reticulum Stress and DiseaseBiologyProteasomeUbiquitinCell biologyProgrammed cell deathUbiquitin-Protein LigasesProtein degradationAutophagyApoptosisGenetics
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References
β-catenin is a target for the ubiquitin–proteasome pathway
The EMBO Journal · 1997 · 2,503 citations
The cyclosome, a large complex containing cyclin-selective ubiquitin ligase activity, targets cyclins for destruction at the end of mitosis.
Molecular Biology of the Cell · 1995 · 755 citations
THE UBIQUITIN SYSTEM
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