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In Vivo Direct Reprogramming of Reactive Glial Cells into Functional Neurons after Brain Injury and in an Alzheimer’s Disease Model

Cell stem cell · 2013 · Vol. 14(2) · pp. 188–202
Ziyuan GuoLei ZhangZheng WuYu‐Chen ChenFan WangGong Chen
Pluripotent Stem Cells ResearchNeurogenesis and neuroplasticity mechanismsNerve injury and regenerationReprogrammingBiologyIn vivoNeuroscienceDiseaseCell biologyPathologyCellMedicineGenetics

MeSH terms

Chondroitin Sulfate Proteoglycan 4Alzheimer DiseaseAnimalsAntigensAstrocytesBrain InjuriesDisease Models, AnimalGlutamatesHumansMice, Inbred C57BLNerve Tissue ProteinsNeurogliaNeuronsProteoglycansMice

Funding

  • National Institutes of Health
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In Vivo Direct Reprogramming of Reactive Glial Cells into Functional Neurons after Brain Injury and in an Alzheimer’s Disease Model · Scinovex