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Treatment of Traumatic Brain Injury in Adult Rats with Intravenous Administration of Human Bone Marrow Stromal Cells

Neurosurgery · 2003 · Vol. 53(3) · pp. 697–703
Asim MahmoodDunyue LuMei LüMichael Chopp

Abstract

These data suggest that the intravenous administration of marrow stromal cells may be a promising therapeutic strategy that warrants further investigation for patients with traumatic brain injury.

Mesenchymal stem cell researchTraumatic Brain Injury and Neurovascular DisturbancesTraumatic Brain Injury ResearchMedicineGlial fibrillary acidic proteinTraumatic brain injuryStromal cellImmunohistochemistrySalinePathologyBone marrowMesenchymal stem cellAnesthesia

MeSH terms

AnimalsBrainBrain InjuriesFemaleInjections, IntravenousMaleMotor ActivityMotor SkillsNerve RegenerationY ChromosomeDNA ProbesBone Marrow TransplantationStromal CellsRats, WistarRats
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