reviewTop 1% cited
The EPR effect for macromolecular drug delivery to solid tumors: Improvement of tumor uptake, lowering of systemic toxicity, and distinct tumor imaging in vivo
Advanced Drug Delivery Reviews · 2012 · Vol. 65(1) · pp. 71–79
Lanthanide and Transition Metal ComplexesElectron Spin Resonance StudiesNanoparticle-Based Drug DeliveryExtravasationIn vivoDrug deliveryToxicityPharmacologyDrugChemistryMedicineElectron paramagnetic resonanceCancer research
MeSH terms
AnimalsAntineoplastic AgentsCapillary PermeabilityHumansNeoplasmsDrug Delivery SystemsMacromolecular SubstancesNanoparticles
Citations
2,312
FWCI
47.42
field-weighted impact
References
95
Percentile
100%
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Citations per year
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References
The EPR effect: Unique features of tumor blood vessels for drug delivery, factors involved, and limitations and augmentation of the effect
Advanced Drug Delivery Reviews · 2010 · 3,472 citations
Tumor Angiogenesis: Therapeutic Implications
New England Journal of Medicine · 1971 · 10,087 citations
Tumor vascular permeability and the EPR effect in macromolecular therapeutics: a review
Journal of Controlled Release · 2000 · 6,447 citations
Redox control of cell fate by MAP kinase: physiological roles of ASK1-MAP kinase pathway in stress signaling
Biochimica et Biophysica Acta (BBA) - General Subjects · 2008 · 493 citations
Openings between Defective Endothelial Cells Explain Tumor Vessel Leakiness
American Journal Of Pathology · 2000 · 1,663 citations
Mechanism of tumor-targeted delivery of macromolecular drugs, including the EPR effect in solid tumor and clinical overview of the prototype polymeric drug SMANCS
Journal of Controlled Release · 2001 · 911 citations
Effects of particle size and surface charge on cellular uptake and biodistribution of polymeric nanoparticles
Biomaterials · 2010 · 2,520 citations
Nanomedicine: current status and future prospects
The FASEB Journal · 2005 · 1,986 citations
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