reviewTop 1% cited
The EPR effect: Unique features of tumor blood vessels for drug delivery, factors involved, and limitations and augmentation of the effect
Advanced Drug Delivery Reviews · 2010 · Vol. 63(3) · pp. 136–151
Nanoplatforms for cancer theranosticsLanthanide and Transition Metal ComplexesMetal complexes synthesis and propertiesExtravasationDrug deliveryVascular permeabilityDrugPharmacologyAngiogenesisMedicineElectron paramagnetic resonanceVasodilationBlood vessel
MeSH terms
AnimalsCapillary PermeabilityExtravasation of Diagnostic and Therapeutic MaterialsHumansNeoplasmsDrug Delivery Systems
Funding
- Ministry of Education, Culture, Sports, Science and Technology
Citations
3,472
FWCI
78.17
field-weighted impact
References
159
Percentile
100%
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Citations per year
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References
Nitric oxide, superoxide, and peroxynitrite: the good, the bad, and ugly
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Tumor delivery of macromolecular drugs based on the EPR effect
Advanced Drug Delivery Reviews · 2010 · 1,993 citations
Angiogenesis in cancer, vascular, rheumatoid and other disease
Nature Medicine · 1995 · 7,654 citations
Mechanism of tumor-targeted delivery of macromolecular drugs, including the EPR effect in solid tumor and clinical overview of the prototype polymeric drug SMANCS
Journal of Controlled Release · 2001 · 911 citations
The dawning era of polymer therapeutics
Nature Reviews Drug Discovery · 2003 · 3,227 citations
Correlation between nitric oxide formation during degradation of organic nitrates and activation of guanylate cyclase
European Journal of Pharmacology · 1987 · 897 citations
Pituitary follicular cells secrete a novel heparin-binding growth factor specific for vascular endothelial cells
Biochemical and Biophysical Research Communications · 1989 · 2,262 citations
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