article Open AccessTop 1% cited
PTP1B Regulates Leptin Signal Transduction In Vivo
Developmental Cell · 2002 · Vol. 2(4) · pp. 489–495
Janice M. Zabolotny(Boston Medical Center)Kendra K. BenceAlain Stricker‐Krongrad(Millennium Engineering and Integration (United States))Fawaz G. HajYongping WangYasuhiko MinokoshiYoung‐Bum KimJoel K. Elmquist(Beth Israel Deaconess Medical Center)Louis A. Tartaglia(Millennium Engineering and Integration (United States))Barbara B. Kahn✉Benjamin G. Neel
Regulation of Appetite and ObesityProtein Tyrosine PhosphatasesBiochemical Analysis and Sensing TechniquesLeptinLeptin receptorBiologyInternal medicineEndocrinologySignal transductionInsulin resistancePhosphorylationProtein tyrosine phosphataseInsulin
MeSH terms
AnimalsHippocampusHypothalamusMolecular Sequence DataObesityProtein-Tyrosine KinasesProto-Oncogene ProteinsTransfectionSignal TransductionWeight GainGene Expression Regulation, EnzymologicProtein Tyrosine PhosphatasesMice, KnockoutCOS CellsLeptin
Funding
- American Diabetes Association
- Israel National Road Safety Authority
- National Institutes of Health
Citations
814
FWCI
11.91
field-weighted impact
References
39
Percentile
99%
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Citations per year
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References
Distributions of leptin receptor mRNA isoforms in the rat brain
The Journal of Comparative Neurology · 1998 · 1,039 citations
Increased Energy Expenditure, Decreased Adiposity, and Tissue-Specific Insulin Sensitivity in Protein-Tyrosine Phosphatase 1B-Deficient Mice
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