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Exosome Delivered Anticancer Drugs Across the Blood-Brain Barrier for Brain Cancer Therapy in Danio Rerio

Pharmaceutical Research · 2015 · Vol. 32(6) · pp. 2003–2014

Tianzhi Yang✉(Husson University)Paige Martin(Husson University)Brittany Fogarty(Husson University)Alison Brown(Husson University)Kayla Schurman(Husson University)Roger Phipps(Husson University)Viravuth P. Yin(Mount Desert Island Biological Laboratory)Paul R. Lockman(West Virginia University)Shuhua Bai(Husson University)

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Extracellular vesicles in disease MicroRNA in disease regulation RNA Interference and Gene DeliveryExosomeMicrovesiclesZebrafishCancer cellCancer researchBlood–brain barrierBrain tumorBiologyCell biologyCancer

MeSH terms

AnimalsAntineoplastic AgentsBlood-Brain BarrierBrain NeoplasmsCapillary PermeabilityChemistry, PharmaceuticalDisease Models, AnimalDoxorubicinEndocytosisHumansNeoplasm TransplantationParticle SizeTechnology, PharmaceuticalTime FactorsZebrafish

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Using exosomes, naturally-equipped nanocarriers, for drug delivery