reviewTop 1% cited

Biology of Incretins: GLP-1 and GIP

Gastroenterology · 2007 · Vol. 132(6) · pp. 2131–2157

Laurie L. Baggio✉(University of Toronto)Daniel J. Drucker(Mount Sinai Hospital)

Diabetes Treatment and Management Peptidase Inhibition and Analysis Pancreatic function and diabetesIncretinMedicineEndocrinologyDiabetes mellitusType 2 diabetes

MeSH terms

AnimalsClinical Trials as TopicDiabetes Mellitus, Type 2Gastric Inhibitory PolypeptideGastrointestinal HormonesGlycated HemoglobinHemoglobinsHumansSignal TransductionReceptors, GlucagonInsulin-Secreting CellsGlucagon-Like Peptide 1

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References

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Preserved incretin activity of glucagon-like peptide 1 [7-36 amide] but not of synthetic human gastric inhibitory polypeptide in patients with type-2 diabetes mellitus.

Journal of Clinical Investigation · 1993 · 1,635 citations

Degradation of glucose-dependent insulinotropic polypeptide and truncated glucagon-like peptide 1 in vitro and in vivo by dipeptidyl peptidase IV.

Endocrinology · 1995 · 1,093 citations

Effects of Exenatide (Exendin-4) on Glycemic Control and Weight Over 30 Weeks in Metformin-Treated Patients With Type 2 Diabetes

Diabetes Care · 2005 · 1,553 citations

Glucagon-like peptide-1(7–36)amide and glucose-dependent insulinotropic polypeptide secretion in response to nutrient ingestion in man: acute post-prandial and 24-h secretion patterns

Journal of Endocrinology · 1993 · 692 citations

Dipeptidyl‐peptidase IV hydrolyses gastric inhibitory polypeptide, glucagon‐like peptide‐1(7–36)amide, peptide histidine methionine and is responsible for their degradation in human serum

European Journal of Biochemistry · 1993 · 1,158 citations

Glucagon-Like Peptides: Regulators of Cell Proliferation, Differentiation, and Apoptosis

Molecular Endocrinology · 2003 · 479 citations

Central administration of GLP-1-(7-36) amide inhibits food and water intake in rats

American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · 1996 · 589 citations

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