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Intrapartum-related neonatal encephalopathy incidence and impairment at regional and global levels for 2010 with trends from 1990

Pediatric Research · 2013 · Vol. 74(S1) · pp. 50–72

Anne CC Lee✉(Brigham and Women's Hospital)Naoko Kozuki(Johns Hopkins University)Hannah Blencowe(London School of Hygiene & Tropical Medicine)Theo Vos(University of Washington)Adil N Bahalim(Global Fund to Fight AIDS, Tuberculosis and Malaria)Gary L. Darmstadt(Bill & Melinda Gates Foundation)Susan Niermeyer(Center for Global Health)Matthew Ellis(University of Bristol)Nicola J. Robertson(London Women's Clinic)Simon Cousens(London School of Hygiene & Tropical Medicine)Joy E Lawn(London School of Hygiene & Tropical Medicine)

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Abstract

Intrapartum-related conditions are a large global burden, mostly due to high mortality in low-income countries. Universal coverage of obstetric care and neonatal resuscitation would prevent most of these deaths and disabilities. Rates of impairment are highest in middle-income countries where neonatal intensive care was more recently introduced, but quality may be poor. In settings without neonatal intensive care, the impairment rate is low due to high mortality, which is relevant for the scale-up of basic neonatal resuscitation.

Neonatal and fetal brain pathology Fetal and Pediatric Neurological Disorders Neonatal Respiratory Health ResearchMedicineNeonatal encephalopathyIncidence (geometry)Case fatality ratePediatricsAsphyxiaBurden of diseaseEncephalopathyDemographyPopulation

MeSH terms

Asphyxia NeonatorumCentral Nervous System DiseasesFemaleHumansMaleMorbiditySex FactorsSocioeconomic FactorsGlobal HealthIncidenceSurvival RateLinear ModelsRisk AssessmentHistory, 20th CenturyHistory, 21st Century