article Open AccessTop 1% cited
The Microbead Occlusion Model: A Paradigm for Induced Ocular Hypertension in Rats and Mice
Investigative Ophthalmology & Visual Science · 2010 · Vol. 51(1) · pp. 207–207
Rebecca M. Sappington✉Brian J. Carlson(Vanderbilt University Medical Center)Samuel D. Crish(Vanderbilt University Medical Center)David J. Calkins(Vanderbilt University Medical Center)
Abstract
These data support a novel and flexible model of modest ocular hypertension with axon loss. The maximal duration of IOP elevation will be further characterized in future studies.
Glaucoma and retinal disordersCorneal surgery and disordersRetinal Diseases and TreatmentsIntraocular pressureOcular hypertensionMicrobead (research)GlaucomaMedicineSalineIsotonic salineOphthalmologyAnimal modelAnesthesia
MeSH terms
AnimalsAnterior ChamberAqueous HumorAxonsDisease Models, AnimalInjectionsIntraocular PressureMaleMice, Inbred C57BLMicrospheresOcular HypertensionOptic NerveOptic Nerve DiseasesPolystyrenesRats, Inbred BN
Funding
- University of Alabama at Birmingham
- Vanderbilt University Medical Center
Citations
398
FWCI
17.12
field-weighted impact
References
30
Percentile
100%
vs. same field & year
Citations per year
References
Relationship Between Intraocular Pressure and Primary Open Angle Glaucoma Among White and Black Americans
Archives of Ophthalmology · 1991 · 1,181 citations
The Ocular Hypertension Treatment Study
Archives of Ophthalmology · 2002 · 3,662 citations
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The Microbead Occlusion Model: A Paradigm for Induced Ocular Hypertension in Rats and Mice
Investigative Ophthalmology & Visual Science · 2010 · 398 citations
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