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MicroRNA-21 (miR-21) represses tumor suppressor PTEN and promotes growth and invasion in non-small cell lung cancer (NSCLC)

Clinica Chimica Acta · 2010 · Vol. 411(11-12) · pp. 846–852
Jiguang ZhangJianjun WangFeng ZhaoQuan LiuKe JiangGuanghai Yang
MicroRNA in disease regulationCancer-related molecular mechanisms researchRNA modifications and cancerPTENmicroRNACancer researchBiologyTransfectionTumor suppressor geneCell growthMetastasisTumor progressionLung cancer

MeSH terms

AgedBinding SitesCarcinoma, Non-Small-Cell LungFemaleHumansLung NeoplasmsMaleMiddle AgedNeoplasm InvasivenessRNA Processing, Post-TranscriptionalBiomarkers, TumorDown-RegulationTumor Suppressor ProteinsMicroRNAsCell Line, Tumor
Citations
556
FWCI
14.45
field-weighted impact
References
59
Percentile
99%
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Cited by
PTEN: Multiple Functions in Human Malignant Tumors
Frontiers in Oncology · 2015 · 458 citations
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