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MicroRNA-21 (miR-21) post-transcriptionally downregulates tumor suppressor Pdcd4 and stimulates invasion, intravasation and metastasis in colorectal cancer

Oncogene · 2007 · Vol. 27(15) · pp. 2128–2136
Irfan A. AsanganiSuhail Ahmed Kabeer RasheedDessislava A. NikolovaJöerg H. LeupoldNancy H. ColburnStefan PostHeike Allgayer
MicroRNA in disease regulationCircular RNAs in diseasesRNA modifications and cancerIntravasationBiologymicroRNAMetastasisCancer researchTransfectionCarcinogenesisUntranslated regionGentamicin protection assayCancer

MeSH terms

AdenocarcinomaAnimalsBase SequenceChick EmbryoHumansMolecular Sequence DataNeoplasm InvasivenessNeoplasm MetastasisSequence Homology, Nucleic AcidTumor Cells, CulturedColorectal NeoplasmsDown-RegulationGene Expression Regulation, NeoplasticGenes, Tumor SuppressorRNA-Binding Proteins

Funding

  • Deutsches Krebsforschungszentrum
  • Alfried Krupp von Bohlen und Halbach-Stiftung
Citations
1,881
FWCI
43.34
field-weighted impact
References
40
Percentile
100%
vs. same field & year
Citations per year
References
MicroRNAs
Cell · 2004 · 34,668 citations
Oncomirs — microRNAs with a role in cancer
Nature reviews. Cancer · 2006 · 7,016 citations
miR-21-mediated tumor growth
Oncogene · 2006 · 1,594 citations
A new mathematical model for relative quantification in real-time RT-PCR
Nucleic Acids Research · 2001 · 34,549 citations
Specificity of microRNA target selection in translational repression
Genes & Development · 2004 · 1,627 citations
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